罗弘

罗弘

中文名 罗弘
毕业院校 湖南农业大学
目录导航

教育经历

  1982年,湖南农业大学 学士

  1987年,湖南农业大学 硕士

  1992年,路易维尔大学 博士

工作经历

 1993-1997 Dana-Farber 癌症研究所和哈佛医学院,博士后

   1997-1999 麻省总医院(Massachusetts General Hospital)和哈佛医学院,博士后

   1999-2000 麻省总医院,助理生物学家

   2000-2004 Texas A&M University 医学院,助理教授

   2004-至今 清华大学教授

研究兴趣、领域

       果蝇的发育生物学:

  JAK/STAT信号途径在果蝇大脑发育中的作用

  JAK/STAT信号途径目标基因的鉴定

  影响果蝇大脑发育的新基因的筛选  

       果蝇大脑发育的调控机制

       细胞极性因子、肿瘤抑制因子、表观遗传因子在大脑发育中的作用

       神经元产生的多样性的调控机制

代表性论文

  1. Wei Wang W, Yonggang Li, Liya Zhou, Haitao Yue, Hong Luo. Role of JAK/STAT signaling in neuroepithelial stem cell maintenance and proliferation in the Drosophila optic lobe. Biochemical and Biophysical Research Communications 410 (2011), 714-720.
  2. Wei Wang, Wenke Liu, Yue Wang, Liya Zhou, Xiaofang Tang, Hong Luo. Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development. Developmental Biology 350 (2011), 414–428.
  3. Hong Luo, Paul E. Rose, Thomas M. Roberts and Charles R. Dearolf. The Hopscotch Jak kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila. Molecular Genetics and Genomics 267(2002), 57-63.
  4. Hong Luo and Charles R. Dearolf. The JAK/STAT pathway and Drosophila development. BioEssays 23 (2001), 1138-1147.
  5. Hong Luo, H. Asha, Lutz Kockel, Tim Parke, Marek Mlodzik, and Charles R. Dearolf. The Drosophila Jak kinase Hopscotch is required for multiple developmental processes in the eye. Developmental Biology 213 (1999), 432-441.
  6. Hong Luo, Paul Rose, Dwayne Barber, William P. Hanratty, Sue Lee, Thomas M. Roberts, Alan D. D’Andrea, and Charles R. Dearolf. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Molecular and Cellular Biology 17 (1997), 1562-1571.
  7. Riqiang Yan, Hong Luo, James E. Darnell, Jr., and Charles R. Dearolf. A JAK-STAT pathway regulates wing vein formation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 93 (1996), 5842-5847.
  8. Hong Luo, William P. Hanratty and Charles R. Dearolf. An amino acid substitution in the Drosophila hopTum-l Jak kinase causes leukemia-like hematopoietic defects. The EMBO Journal 14 (1995), 1412-1420.

个人荣誉

1997-2000, Special Fellow, Leukemia and Lymphoma Society of America, $110,000.

2003-2008, Principal Investigator, Signaling Mechanisms of the Drosophila JAK/STAT pathway, NIH R01GM67019-01, $1,280,400 (Declined in 2004).

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